Heart failure is one of the most frequent causes of hospitalization in Germany. In about half of all cases, the heart’s pumping capacity remains intact. This is known as heart failure with preserved systolic pump function (HFpEF). Unfortunately, HFpEF often goes undiagnosed and in many cases leads to death.

"With DARIO, we want to develop a digital diagnostic traffic light for HFpEF patients in order to detect the disease in an early stage and across all disciplines in future, to predict the course of the disease and to improve treatment success through targeted therapy approaches" explains Dr. Dieter Maier, Director Project Management at Biomax and project leader of DARIO.

The diagnostic traffic light uses predictions based on artificial intelligence. To this end, data from everyday clinical practice and clinical studies as well as findings from doctors’ letters are integrated in DARIO. The latter rely on the medical "standard dictionary" SNOMED CT and are converted into a computer-readable and standardized form by means of text mining. Biomax will use its semantic and technical interoperability platform, the BioXM™ Knowledge Management System, to link all data from various sources. In addition, Biomax will configure the user interface of the diagnostic traffic light to deliver it to the clinic.

DARIO is designed to run for three years. Subsequently, Biomax plans to develop a medical product for the healthcare market based on the results of this novel digital solution approach.

About BioXM™
The BioXM™ Knowledge Management Environment is a fully customizable, comprehensive knowledge management system that enables organizations to conduct more integrated, evidence-based research and development. The BioXM platform provides a central archive of all information that represents the collective knowledge of an organization. While individuals focus on generating knowledge in their specific area of expertise, the entire organization can benefit from this knowledge to make better decisions and pursue smarter strategies.

About SNOMED CT
The Systematized Nomenclature of Medicine – Clinical Terminology (SNOMED CT) is a comprehensive, structured collection of terms used in healthcare. It represents a formal representation system (ontology) for health information, which is now used worldwide to standardize the communication of health data and make it available for automatic evaluations. The introduction of SNOMED CT in Germany is a building block for semantic interoperability in the electronic exchange and use of health data.
Since January 1, 2021, the national competence center for terminologies in the BfArM with the National Release Center (NRC) is responsible for the provision and further development of SNOMED CT in Germany.